Encontram-se abertas na secretaria de pós-graduação do IFUSP as inscrições para o mini-curso de Dicroismo Circular utilizando radiação sincrotron (SRCD): fundamentos e aplicações em sistemas biologicamente relevantes, que sera ministrado dias 24 e 25.08.2016 no IFUSP.
profa. Bonnie A. Wallace - Institute of Structural and Molecular Biology, Birbeck College University of London, UK
prof. Robert W.James - School of Biological and Chemical Sciences, Queen Mary University of London, UK
A ementa do mini-curso encontra-se abaixo.
Maiores informações e cronograma do mini-curso, entrar em contato com profa. Rosangela Itri (itri@if.usp.br); 3091-7012.
Ementa:
1) Introduction to electromagnetic radiation and absorption spectroscopy
2) Fundamentals of Circular Dichroism Spectroscopy (CD)
3) Applications of CD to peptides and proteins:
a) Soluble proteins
b) Membrane proteins
c) Thermal analyses
d) Oriented samples
e) Intrinsically disordered proteins
4) SRCD for biological macromolecules
a) Method and advantages
b) Novel applications
5) Data Collection
a) Instrumentation, calibration and experimental considerations
b) Data processing
6) Methods of analysis
a) Deconvolution methods
b) Data Bases and bioinformatics for analyses
c) The Protein Circular Dichroism Data Bank (PCDDB)
7) Pratical Applications Hands on-Computing
a) Data processing
b) Data analysis with Dichroweb
c) Bioinformatics websites for associated information
d) The PCDDB
